traditional West African food plant Irvingia gabonensis for the treatment of obesity and other

Description

A recent in vitro study indicates that IGOB131, a seed extract of the traditional West African food plant Irvingia gabonensis, favorably impacts adipogenesis (the formation of fat or fatty tissue) through a variety of critical metabolic pathways.

This current study was aimed at evaluating the effects of IGOB131 on body weight and associated metabolic parameters in overweight human volunteers.

The study participants comprised of 102 healthy, overweight and/or obese volunteers randomly divided into two groups. The groups received on a daily basis, either 150 mg of IGOB131 or matching placebo in a double-blinded fashion, 30–60 minutes before lunch and dinner. At baseline, 4, 8 and 10 weeks of the study, subjects were evaluated for changes in anthropometrics and metabolic parameters to include fasting lipids, blood glucose, C-reactive protein, adiponectin, and leptin.

Significant improvements in body weight, body fat, and waist circumference as well as plasma total cholesterol, LDL cholesterol, blood glucose, C-reactive protein, adiponectin and leptin levels were observed in the IGOB131 group compared with the placebo group

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